U 135 Pill (White): Identification, Dosage & Uses

u 135 pill is a widely known antihypertensive medication having Clonidine Hydrochloride 0.1 mg as an active ingredient.

u 135 pill is used to treating the following conditions:

• Hypertension
• Prophylaxis of migraine
• Menopausal flushing
• Vascular headache
• Attention deficit hyperactivity disorder

It is advised to take this medication orally as directed by your doctor. The dosage will depend on the condition and your response to the treatment.

Pill Imprint	u 135 pill
Colour	White
Shape	Capsule-Shaped
Manufacturer/Supplier	Unichem Pharmaceuticals

Other uses of u 135 pills

Clonidine is also used in the treatment of dysmenorrhea, Tourette’s syndrome, and alcohol and opiate withdrawal.

u 135 pill is a prescribed medicine that helps alleviate hot flashes and sweaty nights in women who are at the menopausal stage.

Clonidine is also used as an aid in smoking cessation therapy and to diagnose pheochromocytoma.

Talk to your doctor about the possible risks of using this medication for your condition.

About u 135 pill

Active Ingredient	Clonidine Hydrochloride
Strength	0.1 mg
Pregancy Category	Pregnancy category C
Route of administration	Oral

Dosage of u 135 pill

Follow the instructions given by the doctor, dosage will be decided by the doctor according to your condition and response to the treatment.

• Hypertension – a single dose of u 135 pill
• Prophylaxis of migraine – single pill or half pill a day
• Menopausal flushing – half pill twice a day
• Vascular headache – half pill once or twice a day as per your conditions
• Attention deficit hyperactivity disorder – single pill of u 135 pill once a day

It is strictly advised to take u 135 pill as recommended by your prescribing doctor. 

The dosage of u 135 pill varies according to the condition for which you are taking this pill.

Side effects of u 135 pill

Like other medications, u 135 pill also exhibits some mild to moderate side effects.

Common side effects of u 135 pill are:

1. dry mouth
2. tiredness
3. weakness
4. headache
5. nervousness
6. decreased sexual ability
7. nausea
8. vomiting
9. constipation

If any of these side effects last more than 2 days or cause any problems. Then you should consult your doctor.

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How to store u 135 pill

It is advised to store u 135 pill in the airtight container that comes with it. keep it at room temperature and away from excess heat and moisture.

If your medicine is expired, the best way to dispose of your medication is through a medicine take-back program.

Talk to your pharmacist to learn about take-back programs in your community.

Precautions & warnings

• Tell your doctor if you had any allergic reaction previously to any ingredients of the u 135 pill.
• Talk with your doctor to know about the risks & benefits if you are older than 65 years of age.
• Also, inform your doctor about your current medications & other nutritional supplements to check for any kind of drug-drug interaction.
• You should avoid the consumption of alcohol while taking this pill. alcohol can make the side effects of clonidine worse.
• dizziness, lightheadedness and increased sleeping tendency are common side effects of u 135 pill.
• Take u 135 pill immediately after a meal to reduce the chances of side effects.

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u 135 pill uses in pregnancy

u 135 pill should be used during pregnancy only when the benefits outweigh the risks.

if used during the pregnancy, close monitoring of the pregnant women should be avoided.

According to this recently published study, Clonidine is cleared more rapidly from pregnant women than from non-pregnant women. the study also shows that clonidine was also found in the fetus’ plasma.

u 135 uses in pregnancy

u 135 pill is excreted from breast milk. however, there isn’t enough information about its effect on nursing infants. u 135 pill use is therefore not recommended for breastfeeding.

What happens in case of overdose?

In case of an overdose, you should contact your doctor immediately to avoid further severe complications.

Symptoms of overdose may include the following:

1. Confusion
2. Cold, pale skin
3. Drowsiness
4. Slow heart rate
5. Difficulty breathing
6. Shivering
7. Slurred speech
8. Fainting

Induce vomiting to spill up the unabsorbed drug from the stomach.

Drug interactions of u 135 pill

Drug interactions can change the way your medication works and you might get undesired effects.

Before consuming this pill tell your doctor about your current medications including nutritional & herbal supplements to check drug interactions.

Following class of antihypertensive drugs produces hypotensive agents

1. Diuretics,
2. β-blockers,
3. Vasodilators,
4. Ca antagonists,
5. ACE inhibitors

• Barbiturates – u 135 pill potentiates the CNS depressant effect of barbiturates.
• Mirtazapine – Diminishes antihypertensive effect of u 135 pill.

Pharmacokinetics of u 135 pill

Mechanism of action – in brain stem clonidine stimulates α2-adrenoceptors which leads to reduced sympathetic tone and decreased peripheral resistance, renal vascular resistance, heart rate and blood pressure.

Onset of action – u 135 pill starts its action within 0.5-1 hour and achieves maximum effect within 1-2 hours after administration.

Absorption – u 135 pill well-absorbed from the gastrointestinal tract.

Distribution – u 135 pill Crosses the placenta, enters the breast milk and distributes readily into extravascular sites.

Metabolism – Metabolised in the liver to inactive metabolites; undergoes enterohepatic recirculation.

Excretion – mainly excreted in urine & faeces.

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FAQs of u 135 pill