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M366 Pill – Uses, Dosage, Side Effects & FAQs

M366 Pill

The M366 pill is a prescription for relieving moderate to severe pain. It contains a combination of two potent pain relievers.

This article aims to provide an overview of the M366 pill, including its uses, dosage, side effects, and frequently asked questions.

Whether you are a patient looking to learn more about your medication or a healthcare provider seeking additional information to share with your patients, this article offers valuable insights into the M366 pill. So, read on to learn more.

What is M366 Pill?

What is M366 Pill?
What is M366 Pill?

The M366 pill is a prescription medication that combines Acetaminophen and Hydrocodone Bitartrate. It is an opioid pain reliever used to treat moderate to severe pain. The white, oval-shaped pill has the imprint M366 on one side and is manufactured by Mallinckrodt Pharmaceuticals.

The Acetaminophen component of the pill is a non-opioid pain reliever that helps to increase the effectiveness of Hydrocodone Bitartrate.

Hydrocodone Bitartrate is an opioid that alters how the brain perceives pain. This combination medication is available in multiple strengths, with M366 containing 325 mg of Acetaminophen and 7.5 mg of Hydrocodone Bitartrate.

As with all opioid medications, the M366 pill has the potential for abuse and addiction. It can cause drowsiness, dizziness, and impaired judgment, so avoiding driving or operating heavy machinery while taking it is important.

Patients should take this medication exactly as their doctor prescribes and should not exceed the recommended dosage or duration of use.

If you have any questions or concerns about the M366 pill or other medications, you must consult your healthcare provider or pharmacist for guidance.

Key Benefits & Uses

M366 Pill is a combination medication that contains Acetaminophen and Hydrocodone Bitartrate. The key benefits of this medication include:

  1. Pain relief: Hydrocodone in M366 is a narcotic pain reliever, while Acetaminophen is a non-narcotic pain reliever. Together, they work to provide effective pain relief for moderate to severe pain.
  2. Reducing fever: Acetaminophen is also an effective fever reducer, which can help reduce fever in patients with flu or other illnesses.
  3. Improved quality of life: This medication can improve the quality of life for patients suffering from chronic pain conditions, such as arthritis or back pain.
  4. Convenience: By combining two pain relievers in one pill, patients can take fewer pills and simplify their medication regimen.
  5. Increased functionality: Pain relief can help patients regain mobility and functionality, allowing them to engage in activities they may have had to avoid due to pain.

It’s important to note that while this medication can be effective for pain relief, it can also be addictive and should only be taken under the guidance of a healthcare professional.


The recommended dosage for M366 Pill, which contains Acetaminophen and Hydrocodone Bitartrate 325 mg / 7.5 mg, will vary depending on the patient’s age, weight, and medical conditions.

It is important to follow the dosage instructions a healthcare professional provides or the medication label carefully. Generally, the usual adult dose for pain relief is one tablet every 4 to 6 hours as needed, up to a maximum of 6 tablets in 24 hours.

However, it is important never to exceed the recommended dose as this can lead to serious side effects or overdose.

It is also important to note that this medication should only be taken under the guidance of a healthcare professional and should not be shared with others.

Precautions & Warnings

While taking this medication, certain precautions must be taken to ensure its safe and effective use. Here are some of the precautions that should be followed:

  • Do not take this medication if you are allergic to Acetaminophen, Hydrocodone or any of its inactive ingredients.
  • Do not take this medication if you have severe breathing problems or have recently used alcohol, sedatives, tranquillizers, or other narcotic medications.
  • Do not take more than the recommended dose or for a longer period than prescribed by your doctor. Overdosing on this medication can cause serious harm to your liver and can lead to death.
  • Inform your doctor if you have a history of liver disease or kidney disease or are pregnant or breastfeeding.
  • Avoid alcohol while taking this medication as it can increase the risk of liver damage.
  • Do not share this medication with anyone else, especially those with a history of drug abuse or addiction.
  • Keep this medication out of reach of children and pets.

By following these precautions, you can ensure the safe and effective use of the M366 Pill to relieve pain. Contact your doctor immediately if you experience any adverse effects while taking this medication.

Side Effects of M366 Pill

Like any other medication, it has potential side effects. Here are some common side effects associated with M366 Pill:

Some less common side effects of the M366 Pill include:

  • Severe allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat
  • Slow or shallow breathing
  • Seizures
  • Confusion
  • Hallucinations
  • Unusual thoughts or behaviour
  • Severe stomach pain or diarrhoea

It is important to note that this is not an exhaustive list of side effects. If you experience any unusual symptoms or have concerns about the medication, contact your healthcare provider immediately.

It is also important to follow the prescribed dosage and not exceed it, as this can increase the risk of side effects.

Frequently Asked Questions

  1. What is M366 Pill?

    M366 is a prescription medication that combines Acetaminophen and Hydrocodone Bitartrate. It is used to treat moderate to severe pain.

  2. How does M366 work?

    Hydrocodone is an opioid pain reliever that works by binding to certain receptors in the brain and spinal cord. This reduces the perception of pain. Acetaminophen is a non-opioid pain reliever that increases the body’s pain threshold and reduces fever.

  3. What are the common side effects of M366?

    The common side effects of M366 include dizziness, drowsiness, nausea, vomiting, constipation, and headache.

  4. How often should I take M366?

    M366 should be taken exactly as prescribed by your doctor. The usual dosage is one tablet every four to six hours for pain relief.

  5. Can I take M366 with other medications?

    M366 should not be taken with alcohol or other medications that can cause drowsiness or slow breathing. It is important to inform your doctor about all your medications, including over-the-counter drugs and herbal supplements.

  6. Is M366 addictive?

    Hydrocodone, one of the ingredients in M366, can be habit-forming if taken for a long period or in high doses. Following your doctor’s instructions is important, and taking only what is prescribed.

  7. How should I store M366?

    M366 should be stored at room temperature, away from moisture and heat. Keep it out of reach of children and pets. Unused medication should be properly disposed of according to local regulations.


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