M366 Pill Guide – Things you should know

M366

m366 pill is a white-colored oval-shaped strong opioid analgesic pain killer containing Acetaminophen 325 mg and Hydrocodone Bitartrate 7.5 mg as an active ingredient.

Hydrocodone bitartrate, an active ingredient of the m366 pill belongs to the narcotic analgesic which comes under the controlled substances act.

Pill Name	m366
Colour	white
Shape	oval/elliptical
Active Ingredient	Acetaminophen 325 mg and Hydrocodone Bitartrate 7.5 mg
Supplier	Mallinckrodt Pharmaceuticals

Why m366 pill is prescribed?

m366 pill is a widely known opioid analgesic combination used in the management of moderate to severe pain where normal painkillers do not show any action.

uses of m366 pill:

• Back Pain
• Cough
• Chest Pain
• Nasal Congestion caused by Allergic Rhinitis
• Nasal Congestion caused by Common Cold
• Upper respiratory symptoms caused by Allergic Rhinitis
• Rhinitis caused by Common Cold

How does the m366 pill works?

M366 pill contains Acetaminophen and Hydrocodone which acts in the following ways.

Acetaminophen – it is an analgesic and antipyretic drug which works by reducing the production of prostaglandins in the body which are required to generate pain response in the body.

Hydrocodone  – it is a semisynthetic narcotic analgesic and antitussive similar to the popular drug codeine. It works by mimicking the action of opioid receptors which provides analgesia, drowsiness,  changes in mood, and mental clouding.

Dosage of m366

It is advised to take the m366 pill as per the doctor’s prescription. as he is the right person to check your condition and suggest the best suitable and effective dose.

Twice a day with a minimal interval of 6 hours is the most common dosage given of the m366 pill.

However, your doctor may prescribe a different dose than this according to your condition and response to the treatment.

Never change your dose on your own without consulting your doctor. even if you feel the given dose is not working for you.

Talk to your doctor if you do not see any improvement after taking this pill for more than 10 days.

Contraindications of m366

Patients with past experience of hypersensitivity to any ingredient of the m366 pill like hydrocodone or acetaminophen should avoid this pill. Also note, patients with hypersensitivity to other opioids may exhibit cross-sensitivity to this pill.

Respiratory Depression: consumption of the m366 pill may produce respiratory depression in sensitive patients. It can also cause changes in heartbeats, and rhythm. Talk to your doctor if you have any respiratory issues.

Head Injury: Patients with head injuries may experience worsening in their condition. Consumption of the m366 pill should be avoided in such cases.  

Abdominal Conditions: Patients with abdominal conditions should avoid this pill as it may obscure the diagnosis or clinical course of patients with any acute abdominal conditions.

Drug Abuse: m366 pill contains the opioid drug hydrocodone which comes under controlled substance. Talk to your doctor if you ever had any drug addiction in the past.

Alcohol Warning: You should avoid drinking alcohol while taking m366 pill as it may cause many severe side effects.

Precautions & Warnings of m366 pill

Special  Risk  Patients:  As with any narcotic analgesic pill, the m366 pill should be used with caution in elderly or debilitated patients and those with severe impairment of hepatic or renal function, hypothyroidism, and Addison’s disease.

Cough Reflex: patients who have recently undergone lung surgery or have pulmonary disease should be cautious while taking the m366 pill.

Addiction: people with past history of drug abuse or severe alcoholism should avoid taking the m366 pill as it may cause addiction.

Use in Pregnancy & Breastfeeding

m366 is not usually recommended during pregnancy, it is a pregnancy category c pill that may cause harmful effects on the fetus.

Nursing mothers should also avoid this m366 as some extent of drugs get passed through breastmilk and may cause withdrawal symptoms in their babies.

Talk to your doctor and pharmacist to know in detail about the benefits and risks of the m366 pill during pregnancy or breastfeeding.

Side Effects of m366

Like any other medication, the m366 pill also causes mild to moderate side effects. however, you should not worry about them as they are very rare and most people don’t even get them.

Common side effects:

• lightheadedness, 
• dizziness, 
• sedation, 
• nausea and vomiting.

Most of these side effects usually go away within a day as our body gets used to them. however, you should contact your doctor if they become troublesome in your day-to-day activities.

Nervous system side effects: Drowsiness, mental clouding,  lethargy,  impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, and mood changes.

Gastrointestinal  System: Prolonged administration of the m366 pill may produce constipation.

Allergic reactions: skin rash, thrombocytopenia, agranulocytosis.

Drug Interactions of m366

Drug interactions can change the way our medication works and may produce some undesired effects.

• butorphanol,
• nalbuphine,
• pentazocine,
• naltrexone,
• samidorphan,
• alprazolam,
• lorazepam,
• zolpidem,
• carisoprodol,
• cyclobenzaprine,
• cetirizine,
• diphenhydramine.

Also, inform your doctor about any of the other ongoing medications including herbal and nutritional supplements to avoid any interactions.

Who supplies the m366 pill?

M366 pill is supplied by Mallinckrodt Pharmaceuticals as white,  capsule-shaped tablets containing Acetaminophen 325 mg and Hydrocodone Bitartrate 7.5 mg with m366 imprint.

Storage of m366

Store m366 pill in a tight, light-resistant container as defined in the USP. Store it away from direct sunlight or moist areas.

Frequently Asked Questions