The “1 2 pill,” commonly imprinted as I-2, is a widely available over-the-counter medication containing 200 mg of ibuprofen, a nonsteroidal anti-inflammatory drug (NSAID).
Identification and Appearance
This pill is typically a round, brown or orange tablet with a smooth coating and the imprint “I-2” on one side, as required by FDA guidelines for identification. It helps distinguish it from other medications in pill identifier tools. Manufactured by various generic producers, it’s sold under brands like Advil or Motrin equivalents.
Mechanism of Action
Ibuprofen in the I-2 pill inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin production—chemicals that trigger pain, inflammation, and fever. Effects begin within 30-60 minutes and last 4-6 hours. Unlike opioids, it carries no addiction risk and minimal abuse potential.
Common Uses
It’s primarily for mild to moderate pain relief, including headaches, toothaches, menstrual cramps, muscle aches, back pain, and minor arthritis. The pill also lowers fever from colds or flu and reduces inflammation from injuries. Always follow dosing: adults typically take 1 pill every 4-6 hours, not exceeding 6 per day.
Dosage and Administration
Take with food or milk to minimize stomach upset; swallow whole with water. For children, consult a doctor based on weight, as it’s not always suitable. Do not exceed recommended doses to avoid risks.
Side Effects and Precautions
Common side effects include stomach pain, heartburn, nausea, or dizziness. Serious risks involve gastrointestinal bleeding, ulcers, heart issues, or kidney problems, especially with long-term use or in high-risk groups like the elderly. Avoid if allergic to NSAIDs, pregnant (third trimester), or with ulcers, asthma, or heart disease; consult a doctor.
Safety Tips and Interactions
Limit alcohol intake and stay hydrated. It interacts with blood thinners, other NSAIDs, steroids, or blood pressure meds—check with a pharmacist. Not for chronic use without medical advice; alternatives like acetaminophen may suit some better.