The 024 pill is a 10 mg tablet of baclofen, a prescription skeletal muscle relaxant manufactured by TruPharma LLC, identifiable by its white, round shape with “024” imprinted on one side and a score line on the other.
Primary Medical Uses
Baclofen treats spasticity, characterized by muscle stiffness, tightness, spasms, and pain, primarily from multiple sclerosis (MS), spinal cord injuries, or other spinal cord diseases. It acts on nerves in the spinal cord to reduce spasm frequency and severity, improving mobility and relieving discomfort. Patients with reversible spasticity benefit most, as it helps restore function without weakening muscles.
Off-Label Applications
Baclofen sees off-label use for musculoskeletal pain, gastroesophageal reflux disease (GERD), and alcohol use disorder, where it may reduce cravings by mimicking GABA to influence mood and dopamine levels. Evidence supports its role in addiction treatment by easing withdrawal symptoms, though it’s not FDA-approved for these. Use only under medical supervision for non-approved indications.
Dosage and Administration
Typically taken three times daily at even intervals, the 10 mg dose requires exact adherence to prescription—do not exceed or skip without consulting a doctor. Abrupt cessation risks severe withdrawal like seizures, hallucinations, fever, or muscle rigidity. Start low and titrate based on response; available in 10 mg and 20 mg strengths from the same manufacturer.
Common Side Effects
Frequent effects include drowsiness (up to 63%), dizziness (5-15%), weakness (5-15%), and nausea (4-12%). Less common are constipation, hypotension, urinary frequency, and rash. Monitor for genitourinary issues like retention or impotence.
Overdose Risks and Precautions
Overdose symptoms encompass drowsiness, coma, seizures, respiratory issues, vision problems, and muscle hypotonia. Vulnerable groups—elderly, renal-impaired, or those on CNS depressants—face heightened risks. Avoid alcohol; it amplifies sedation.
Mechanism of Action
Baclofen, a GABA-B receptor agonist, inhibits excitatory neurotransmitter release at the spinal level, easing spasticity without full muscle paralysis. Unlike other relaxants, it targets the central nervous system specifically.
Role in Addiction Treatment
In alcohol dependence, baclofen curbs intake and cravings via GABAergic modulation, positioning it as an emerging adjunct therapy alongside standard options like naltrexone. Studies indicate reduced consumption, though dependency can develop with misuse. Seek professional addiction care for safe integration.